Evaluation of acidosis in brain infarction with magnetization transfer ratio asymmetry (MTRasym) and magnetization transfer and relaxation-normalized amide proton transfer rate (MRAPTR) in amide proton transfer-weighted MRI and its influencing factors.

Li, Huan; Singh, Tanoj Bahadur; Liu, Ting; Wang, Tianhao; Huang, Danni; Wu, Yin; Yin, Jianzhong

doi:10.1007/s00234-026-04142-1

Evaluation of acidosis in brain infarction with magnetization transfer ratio asymmetry (MTRasym) and magnetization transfer and relaxation-normalized amide proton transfer rate (MRAPTR) in amide proton transfer-weighted MRI and its influencing factors.

2026-08-15, Neuroradiology (10.1007/s00234-026-04142-1) (online)
Huan Li, Tanoj Bahadur Singh, Ting Liu, Tianhao Wang, Danni Huang, Yin Wu, and Jianzhong Yin (?)

To investigate the sensitivity of the magnetization transfer ratio asymmetry (MTRasym) and magnetization transfer and relaxation-normalized APT rate (MRAPTR) in detecting the tissue acidosis in ischemic stroke, and to assess the influence of infarct volume, apparent diffusion coefficient (ADC), and regions of interest (ROI) position.

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Evaluation of acidosis in brain infarction with magnetization transfer ratio asymmetry (MTRasym) and magnetization transfer and relaxation-normalized amide proton transfer rate (MRAPTR) in amide proton transfer-weighted MRI and its influencing factors.