Chronic nicotine vapor-induced enhancement of ethanol drinking-in-the-dark is associated with reduced medial prefrontal cortical activity.
2026-08-15, Psychopharmacology (10.1007/s00213-026-07147-z) (online)Timothy G Freels, Jennifer Li, Rebecca G Pavchinskiy, Rubing Zhao-Shea, Gilles E Martin, and Andrew R Tapper (?)
Nicotine vaping is associated with increased alcohol use, including binge drinking, yet the neurobehavioral mechanisms underlying nicotine-alcohol interactions remain poorly understood due to limited translational preclinical models capturing intrapulmonary nicotine exposure effects on binge-like ethanol intake.
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